The Brit's departure was announced by the reigning constructors' champions on their official website - who revealed he was poised to take over as team principal at Audi - but the news wasn't confirmed by the F1 newcomers until later in the day.
Having completed their takeover of Sauber, the German outfit are preparing for their introduction to the sport in 2026 by securing a number of key signings ahead of their much-anticipated bow.
In a statement posted on Audi's official website, CEO Gernot Dollner expressed his excitement regarding the team's future.
“I am delighted that we have been able to gain Jonathan Wheatley as Team Principal for our future Formula 1 team,” he said.
“Jonathan has played a major part in many Formula 1 race victories and World Championship titles in his Formula 1 career so far, and has extensive experience in the paddock.
"He is a very valuable addition to our team.“
He continued: “With the appointment of Jonathan and Mattia we have taken a decisive step towards our entry into Formula 1.
“I am convinced that with the two of them, we have been able to combine an extremely high level of competence for Audi.
"Their experience and their ability will help us to get a foothold quickly in the tough competitive world of Formula 1.“