That shock announcement followed ongoing speculation regarding team principal Christian Horner over allegations of misconduct, something he was cleared of after an internal investigation, and he continues to deny.
Horner's 'inappropriate behaviour' saga that has rumbled on for months has caused uncertainty amongst the team, with suggestions that Max Verstappen may also be looking to move on.
Speaking to ESPN, Domenicali admitted the increased interest being generated in F1, including from the ongoing saga at Red Bull, could prove to be a positive thing as the sport builds for the future.
“I would say these are all things that are subjects that, in a different way, have attracted the attention of the people and, at the end of the day, there are things related to teams, related to people, there are things related to the sport, related to something that will happen next year.
"So all the stuff is really taking the attention of all the people that are not totally focused on Formula 1.
"That’s why it’s a moment that we need to respect and a moment that we need to keep investing for our future because we’ve never been so strong."
On the importance of transparency regarding Horner, the Italian added: “For sure it’s important, but it’s important to rely on the fact that this is a matter related to business, to company, to teams that they have their internal compliance and procedures.
"We don’t know the facts because we are not entitled to do but for sure, I think that these are relevant points.”