The departure could come due to differences in views with current Audi CEO Gernot Dollner over the company's future.
According to a report from German newspaper Bild, Hoffmann's long-term contract as CDO, signed last year, may be cut short as he's held responsible for Audi's struggling sales and delays in model releases.
The Audi Supervisory Board is set to discuss Hoffmann's situation on Thursday, with the Volkswagen Group's Supervisory Board expected to make the final decision in early March.
The potential departure of Hoffmann could impact Audi's F1 plans, as Dollner contemplates moving him to the project. Hoffmann played a pivotal role in developing Audi's F1 entry for 2026, initially announced during the 2022 Belgian Grand Prix.
Dollner publicly confirmed the plan in December 2023, but speculations persist about the company's commitment, possibly tied to Dollner's openness to selling Sauber shares, providing a financial exit strategy for Audi.
This uncertainty jeopardises Sauber's ability to attract top talent and the investment necessary for success in F1.
Reports of Hoffmann's potential move are as yet unverified and a spokesperson had previously told Bild Zeitung: "As a matter of principle, we do not comment on personnel matters."