The only Ferrari driver remaining on the grid, Sainz, had a less-than-exciting race in Sao Paulo, finishing in sixth place.
And both drivers have now pointed to different issues with their cars as the primary reason behind their poor results.
Taking to their respective social media accounts, the two drivers shared their disappointment with the results in Brazil and offered explanations.
"Disappointed to say the least," Leclerc said. "Lost the power steering and the engine power on the formation lap. It hurts because today was a great opportunity for us."
Sainz posted a similar message to his Ferrari teammate but took a more forward-looking approach, expressing his anticipation for the upcoming race in Las Vegas rather than dwelling on the Brazil result.
"Difficult day," Sainz said. "Struggled with starts due to a clutch issue and unfortunately P6 was the maximum.
"Big shame for Charles as today we could’ve scored important points against Merc. Time to recharge batteries and come back stronger in Las Vegas."
Fight for P2
Ferrari are currently engaged in a battle with Mercedes for second place in the constructors' championship, sitting 20 points behind as they approach the final two races of the season.
However, Sainz acknowledged that this race could have been crucial for the Scuderia's objectives if both drivers had been in the race, especially considering George Russell's DNF during the race.